Hamburg and the enlarged EEC

The EEC syndrome and its ocular manifestations.

The EEC syndrome (ectrodactyly or lobster-claw deformity, ectodermal dysplasia, and cleft lip and palate) is a rare disorder with autosomal dominant inheritance, variable expression, and in some families lack of penetrance. We present the findings in five cases with emphasis on the ocular findings. Lacrimal surgery was performed on three patients with good results in each case. We also report t...

The Hamburg Metaphor Database

This article presents the Hamburg Metaphor Database project, an online database of French and German metaphors which came into being in 2002. In this database, metaphors appearing in different domain-specific corpora collected from mass media are available. The metaphors are annotated with lexical and conceptual information according to standard resources of the field: the EuroWordNet database ...

From the Dermatologikum Hamburg: Quiz

A 48-year-old woman presented herself with an erythematous macule on the extensor surface of the right thigh. The lesion had been present for years, but recently the patient noticed some increase in size and changes in the coloration. This had prompted her to see a dermatologist (Figure 1). A biopsy was taken and photomicrographs are presented in Figures 2A-I. What is your diagnosis? Answer and...

The p63 gene in EEC and other syndromes.

Several autosomal dominantly inherited human syndromes have recently been shown to result from mutations in the p63 gene. These syndromes have various combinations of limb malformations fitting the split hand-split foot spectrum, orofacial clefting, and ectodermal dysplasia. The p63 syndrome family includes the EEC syndrome, AEC syndrome, ADULT syndrome, limb-mammary syndrome, and non-syndromic...

Biological exposure limits: the fetus and EEC politics.